Inhaladores de acción larga

Diego Severiche Hernández, Diego F Severiche Bueno, Daniel Felipe Severiche Bueno, María Teresa Vargas Cuervo

Resumen


Hoy día, en el mundo, los inhaladores de acción larga son herramientas fundamentales para el tratamiento de las enfermedades broncoobstructivas. Su uso está avalado por consensos internacionales ampliamente difundidos y reconocidos mundialmente, como son las Guías GINA 2017 y las Guías GOLD 2017, entre otros. En Colombia, desde hace varios años, la comunidad médica dispone de varias presentaciones comerciales de inhaladores solos o en diferentes combinaciones. Por tanto, se consideró pertinente realizar una revisión de los conceptos fisiológicos fundamentales, de los principios farmacológicos, de los mecanismos de acción, de la farmacodinamia y farmacocinética. Igualmente, con base en la evidencia disponible al momento de la realización de este artículo, se revisarán las indicaciones clínicas para su uso en las diferentes enfermedades broncoobstructivas.

Palabras clave


broncodilatadores; anticolinérgicos; betaagonistas; mecanismo de acción; farmacodinamia; farmacocinética

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Referencias


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DOI: http://dx.doi.org/10.30789/rcneumologia.v29.n2.2017.265

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